Dry granulation is a common process used in the pharmaceutical industry for the production of OSD forms such as tablets and capsules.
It differs from Wet Granulation in that it does not use a liquid to bind the various excipients and API together to form agglomerated granules. Instead, it uses compression to force the different particles together; typically forming ‘ribbons’ or ‘slugs’. These ‘ribbons’ or ‘slugs’ are then milled and can be compressed into tablets or capsules.
The most common dry granulation equipment is a roller compactor or slugging machine.
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