Pharmaceutical Conical Mills

Milling can involve the reduction of active ingredients (API’s), bulk pharmaceuticals (BPI’s) and excipients such as lactose, HPMC (hydroxypropylmethyl cellulose) and others. In most applications, including where granulated powders are used, material will need to be milled in order to provide a specific particle size range which will allow for subsequent manufacturing processes (e.g. blending and compression)

Grinding particles to a specified size is often necessary to increase surface area and improve formulation dissolution properties. By maintaining a consistent average particle size distribution (PSD) for the formulation, a better quality mixture is achieved for creating oral solid dosage forms such as tablets and capsules. Cone mills are also ideal for delumping, deagglomeration and mixing materials involved during pharmaceutical powder processing.

Hanningfield’s pharma milling and grinding equipment delivers consistent results for a range of applications, including wet and dry milling.

Ideal for bulk pharmaceuticals, foods and contamination-sensitive chemicals, the sanitary unit is suitable for wet and dry milling, pre-conditioning and de-agglomerating of a wide range of bulk products.

Material is fed by gravity or vacuum conveying system into a central milling chamber in which a rotating impeller accelerates it centrifugally against and through apertures in a conical screen, and then into a receptacle below the milling chamber.

Conical screens with round, square or raised lip (cheese grater) perforations can be changed rapidly and are offered with apertures from 150 micron for fine/dry de-agglomeration, up to 25 mm for wet granulation.

Constructed of 304 or 316 stainless steel to sanitary or industrial standards, the mill is top-driven by a belt drive and equipped with fully interlocked moving components with time-delay function for operator safety.  Explosion-containment versions are also available.

Gently grinds materials into uniform particle sizes with minimal fines without the noise, dust, product build-up or heat generation associated with traditional mills.