Bulk powder pharmaceuticals are typically milled during processing to achieve a required particle size. For example, lactose, sucrose, glucose, dextrose and sorbitol are often used as bulk powders / excipients to accurately dose potent ingredients and often require milling.
Usually bulk powders agglomerate during transport and storage and in most applications, including where granulated powders are used, the material will need to be milled prior to subsequent downstream processes (e.g. blending and compression) to improve its flowability. This de-agglomeration step can be a time consuming process and cause a bottleneck in production. Finding a solution to the de-lumping of excipients which allows a high throughput can dramatically improve system efficiency.
Conical Mill (Uni-Mill) for Bulk Powder Processing
A conical mill / grinder is a quick and reliable solution to re-powderise bulk powder, creating a uniform and lump-free consistency. The excipients are reduced to a specific particle size by compressing and shearing the particles between the impeller and the surface of the screen.
The Uni-Mill under-driven models are designed with an optimal, spacer-less gap (to avoid metal-to-metal contact) which enables fast and easy tooling changes and ensures the material is processed efficiently, using the closest possible gap, every time. The Uni-Mill series offers full scalability from laboratory to pilot to production.
Other benefits of the under-driven conical mill includes a high throughput (due to the in-line inlet and outlet), a compact and space-saving design, and an improved sanitary construction (compared to over-driven conical mills).
Features:
> Stainless steel construction (with 316L contact parts)
> All seals FDA compliant (silicone, PTFE etc.)
> No metal-to-metal contact
> Easy-clean, GMP design (with optional features such as detachable millhead for autoclave or CIP/WIP)
> ATEX (ex-proof) versions available
View our Conical Mills (Under-Driven) product page for more information.
Get in Touch
If you would like to speak to one of our experts regarding our Conical Mills or you would like a quote for one of our products, send us a message using our Contact Form or call us on +44 (0)1702 549 777.
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